At this time, however, all practical embodiments of MRI require at least some degree of gradient encoding, and this in turn sets a lower limit of about 100 ms for Vemurafenib cell line volume acquisition. A novel formulation of MRI is proposed here which is given the acronym ULTRA (Unlimited Trains of Radio Acquisitions). In the preferred embodiment ULTRA is completely free of gradient reversals, which allows for signal acquisition from the entire object volume simultaneously. This permits a rate of signal acquisition that is increased hundreds of times compared with existing techniques, with full 3-D imaging in as little as one millisecond. The proposed detector now resembles a holographic recording. “
“Early recognition

of complications during intracranial neuroendovascular

interventions is important for medical decision making and prompts administration of life-saving treatments. Low contrast imaging (LCI) provides computed tomographic (CT)-like images of anatomical brain structures, capable of detecting hydrocephalus and intracranial hemorrhage complications. We present our early experience with LCI using the Toshiba Infinix-i biplane angiographic suite during neurointerventional cases, including acute stroke interventions, aneurysm embolization, and subarachnoid hemorrhage management. Six patients underwent LCI during various neuroendovascular procedures. We describe clinical and imaging findings and provide visual comparison of LCI with conventional noncontrast cranial CT imaging. Our initial experience shows that LCI is capable of detecting or excluding intracerebral hemorrhage and hydrocephalus during neurointerventional procedures as well as confirming ventriculostomy catheter selleck see more placement when compared to noncontrast CT imaging. Motion artifact is a major limitation associated with this technology and can be overcome in part by performing shorter duration rotation sequences. LCI is a promising tool in the arsenal of a neuroendovascular interventionist, especially when a complication is suspected during an intervention,

potentially obviating the need for immediate transfer of the patient to a conventional CT scanner. Further studies comparing LCI with conventional noncontrast CT imaging are necessary. “
“18F-fluoromisonidazole (FMISO) positron emission tomography (PET) is used to image metabolically compromised but viable hypoxic tissue. We hypothesized that FMISO PET might predict early infarct growth in acute ischemic stroke patients with perfusion-diffusion mismatch in magnetic resonance imaging (MRI). We prospectively enrolled acute ischemic stroke patients who visited the emergency room within 48 hours after stroke onset and had perfusion-diffusion mismatch (>20%), as shown MRI. Infarct growth was defined as >20% increase of initial infarct volume or >5 mL in follow-up diffusion-weighted image 5 ± 2 days after stroke. The association between FMISO uptake and infarct growth was explored. Of 19 enrolled patients, 10 (52.