SVR12 data will be available for all patients on 12 week treatments and EOT data will be available for all patients on 24 week treatments at the meeting. Disclosures: Steven L. Flamm – Advisory Committees or Review Panels: Gilead, Bristol Myers Squibb, AbbVie, Janssen, Salix; Consulting: Merck, Janseen, Bristol Myers Squibb, AbbVie, Salix, Gilead; Grant/Research find more Support: Janssen, Bristol Myers Squibb, Merck, Vertex, Gilead, AbbVie, Boehringer Ingelheim; Speaking and Teaching: Salix Bruce R. Bacon – Advisory Committees or Review Panels: Bristol-Myers Squibb, Kadmon, Janssen; Consulting: Merck, ISIS; Grant/Research Support: Merck, Bristol-Myers Squibb, Kadmon, AbbVie; Speaking and Teaching: Merck, Kadmon,

Ribociclib solubility dmso AbbVie, Salix, Janssen Douglas Dieterich – Advisory Committees

or Review Panels: merck, Idenix, Jans-sen ; Consulting: Gilead, BMS Kris V. Kowdley – Advisory Committees or Review Panels: AbbVie, Gilead, Merck, Novartis, Trio Health, Boeringer Ingelheim, Ikaria, Janssen; Grant/Research Support: AbbVie, Beckman, Boeringer Ingelheim, BMS, Gilead Sciences, Ikaria, Janssen, Merck, Mochida, Vertex Eric Lawitz – Advisory Committees or Review Panels: AbbVie, Achillion Pharmaceuticals, BioCryst, Biotica, Enanta, Idenix Pharmaceuticals, Janssen, Merck & Co, Novartis, Santaris Pharmaceuticals, Theravance, Vertex Pharmaceuticals; Grant/Research Support: AbbVie, Achillion Pharmaceuticals, Boehringer Ingel-heim, Bristol-Myers Squibb, Gilead Sciences, GlaxoSmithKline, Idenix Pharmaceuticals, Intercept Pharmaceuticals, Janssen, Merck & Co, Novartis, Presidio, Roche, Santaris Pharmaceuticals, Vertex Pharmaceuticals ; Speaking and Teaching: Gilead, Kadmon, Merck, Vertex Scott Milligan -

Grant/Research Support: Gilead Naoky Tsai – Advisory Committees or Review Panels: Gilead, Vertex; Consulting: BMS, Gilead, Merck; Grant/Research Support: BMS, Gilead, Genentech, Vertex, Novartis, GSK, Bayer, Abbvie, Janssen, beckman; Speaking and Teaching: BMS, Gilead, Genentech, Vertex, Merck, Salix, Bayer, Janssen The following people have nothing to disclose: Zobair Younossi BACKGROUND: The optimal antiviral therapy for HCV infection in HD patients remains to be established. There are no data on the use of new direct-acting antiviral agents in patients with end-stage 上海皓元 renal disease on HD but studies are ongoing. Safety and efficacy data of IBT in KT recipients with non functional grafts on HD are scarce but case reports have shown a high risk of graft intolerance syndrome of the failed kidney allograft in HD patients treated with IBT. AIMS: 1) To evaluate the efficacy and safety of IBT in KT recipients with failed kidney allograft on HD. 2) To compare the risk of GIS between KT recipients with failed kidney allograft on HD undergoing antiviral therapy and untreated patients. METHODS: Retrospective analysis of KT recipients who started HD between January 1999 and December 2013 at Hospital Clinic Barcelona.