e., checking orthographic legality, determining word status, and checking inter-word compatibility); and (2) proofreading for wrong-word errors should involve less reduction

of deeper linguistic processing (both lexical and sentence level). With these considerations in mind, we now lay out a theoretical framework within which potential differences between Enzalutamide cost various “reading” tasks, including normal reading for comprehension, proofreading to catch nonwords, and proofreading to catch wrong words, can be understood. This framework is agnostic as to the specific model of eye movement control in reading (e.g., Bicknell and Levy, 2010, Engbert et al., 2005, Reichle et al., 1998, Reichle et al., 2003 and Schad and Engbert, 2012) assumed, although it should be noted that any complete model of reading must ultimately

be able to account for task differences in reading behavior. Our starting desideratum is that any type of reading—be it normal reading, scanning (skimming the text to find keywords), or proofreading—must involve some combination of (1) identifying words and (2) combining the meanings of those identified words to recover sentence meaning. BMS-387032 ic50 Each of (1) and (2) can be further broken into different components (Table 1). Word identification involves both recognition of word-form and access of lexical content. Word-form recognition can involve both decisions Thiamet G about whether or not the letter string is a word and, furthermore, what exact word it is. For example, wordhood assessment, which

we define as recognizing whether the letter string has a legal (known) orthographic entry (similar to the “orthographic checking” process hypothesized by Kaakinen & Hyönä, 2010) is most obviously relevant for proofreading, but is also relevant even for normal reading since the reader must be able to deal with novel words. We define form validation, on the other hand, as recognizing the specific sequence of letters constituting the word currently being read. Wordhood assessment and form validation are logically distinct. A reader may, for example, conclude that an incompletely identified letter string such as “qo###” is not a word (wordhood assessment without complete form validation), and may also correctly identify the exact letter sequence of a word such as “aortas” while failing to successfully match the sequence to an entry in his/her mental lexicon (correct form validation but incorrect wordhood assessment). Content access involves retrieving word meaning and grammatical properties. Sentence-level processing includes combining individual words’ content into larger, phrasal units (integration) and also assessment of whether each individual word is compatible with the rest of the sentence (word-context validation; essential for many types of error correction).