A smooth surface allows for the growth of pseudomorphic
low-indium InGaN, whereas a rough surface promotes the formation of a relaxed high-indium InGaN layer. (c) 2011 American Institute selleck of Physics. [doi: 10.1063/1.3626434]“
“Aims: A significant proportion of patients with head and neck squamous cell carcinoma are unsuitable for radical treatment due to factors including tumour stage, performance status and co-morbidity. Palliative radiotherapy has a useful role in the control of local symptoms. This study documented the outcome with split-course hypofractionated radiotherapy.
Materials and methods: Thirty-three previously untreated patients with head and neck squamous cell carcinoma were treated with palliative intent with split-course radiotherapy, with an initial 20 Gy in five fractions over 1 week, a 2 week gap, and then a further 20 Gy in five fractions over 1 week at the Yorkshire Cancer Centre between January 2004 and December 2007. Data were collected retrospectively from case notes and radiotherapy
records.
Results: Thirty (91%) patients had stage IV A-B disease. World Health Organization performance status was 2 or 3 in 19(58%) patients. The median age was 76 years (range 48-91 years). Twenty-five (76%) patients were men. Symptomatic improvement was reported in 26 (79%) patients at 4-6 weeks of follow-up. Thirteen
(39%) patients had a complete tumour response and 11(33%) patients had Selleckchem RG 7112 a partial response as assessed clinically, and RSL3 nmr in some cases radiologically. The median overall survival was 9 months (range 3-43 months). Progression-free survival at 1 and 2 years was 35 and 25%, respectively. Overall survival at 1 and 2 years was 42 and 34%, respectively. Treatment was generally well tolerated; admission for nasogastric feeding and/or supportive care was required in only six patients. Radiation Therapy Oncology Group grade 3 toxicity was documented for skin in one patient, for mucosa in two patients and for oesophagitis in three patients.
Conclusion: Split-course hypofractionated radiotherapy is an effective palliative regimen with acceptable toxicity. (C) 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.”
“As grain prices have increased dramatically in the past year, understanding the fundamental genetic, cellular, and biochemical mechanisms responsible for feed efficiency (FE; g of gain/g of feed) or residual feed intake (RFI; an alternative feed efficiency trait that quantifies interanimal variation in DMI that is unexplained by differences in BW and growth rate) in livestock and poultry is extremely important with respect to maintaining viable meat production practices in the United States.