In addition, risperidone or quetiapine. However Essock et al. reported that patients assigned to a switch to monotherapy shorter time to discontinuation for all causes than those assigned to remain on display polypharmacy. These studies were indicators of what can be done with combinations of antipsychotics in patients in chronic phase. In patients with acute phase, However, controlled trials Strips atm protein randomized second-generation antipsychotics combinations have not yet been reported. In the halls of the acute emergency phase and not all patients respond to antipsychotic monotherapy, and we are often confronted with difficulties in the management of psychotic and aggressive patients. Since the non-reaction to the early to predict a standard dose of risperidone which subsequently Reaction k can, Ma took Take to respond results in patients not to start risperidone is more reasonable to improve.
We have therefore investigated whether the Erh Increase the F We prospectively with olanzapine is better than a Erh Increase the dose of risperidone in schizophrenic patients show acute non-response at the start of risperidone. This study was carried out with urgency on the basis of newly admitted patients, without the support of pharmaceutical Zibotentan ETA-receptor inhibitor companies, what the real world of practice. Second Methods 2.1. Setting and participants of the 63 psychiatric emergency service by the Japanese government makes Chtigt, were 18 in this study. These neighborhoods are all over Japan to the, precious metals, were responsible for the local emergency numbers.
Most of these recordings h Kenh Accounted Verhaltensst user Changes Notf Lle and approximately 60% were brought by the police. All were involuntary admissions as an immediate danger to themselves or others, according to 1995 law on mental health and welfare of the mentally handicapped. Details of the clinic will be described elsewhere. After beh North part guidelines, psychiatric emergency service in Ballungsr Umen and local in the last 16 years have been continuously expanded. The quality of t of sites and patients in this study was therefore consistent. This activity t was carried out by Japan acute phase of schizophrenia Trial Study Group. W During the study period was between 1 July and 31 October 2010, recorded a total of 786 patients and evaluated for the F Rderf Ability.
Suitable patients were at the age of 18 64 years, newly classified as Notf Lle taken up, and fulfill the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision of the schizophrenia, schizophrenic St Tion or schizoaffective St Tion. Patients with obvious complications such as liver, kidney failure, heart failure, respiratory failure, or diabetes mellitus were excluded because the patients who were pregnant or wanted to become pregnant. 2.2. Study design All study protocols by the ethics Commission were approves at each site was a written consent after Aufkl Tion of patients or its related laws representatives will receive. Patients taking oral medication were denied initially Highest treated with injections. After resolution and high agitation, the investigators divided patients invited verbally and in writing about the study and to participate. The patients were treated with oral risperidone at flexible doses of 2 weeks and then treated according to size Enordnung the Clinical Global Impressions Improvement divided into