Results of both 5-MeC staining and SC-WGBS indicated that no significant difference had been discovered amongst the F_GV team and also the V_GV team, whilst the methylation amount of the V_MII group was substantially lower than that of the F_MII group. Moreover, supplementation of 2μM resveratrol (Res) in IVM method considerably improved maturation and development ability of vitrified GV oocytes by restoring their DNA methylation levels.Our results provide an efficient approach to improve the maturation and fertilisation capability of vitrified GV oocytes.A retrospective analysis ended up being carried out on 11 cases of Masson’s tumefaction admitted to Liaocheng People’s Hospital from January 2010 to July 2021. Among them, there have been 4 guys and 7 females, elderly from 14 to 62 years, with a medical reputation for 1 to two years. Most of the clients complained of pressing the size beneath the epidermis. In this team, 9 instances were pure type, 1 situation had been combined type and 1 case ended up being extravascular type. Ultrasound imaging can reflect the attributes of Masson’s cyst to some extent, which has a particular worth into the analysis, classification and differential diagnosis.Objective to research the effect associated with quantities of myelosuppression in the curative effect and prognosis of triple-negative cancer of the breast with neoadjuvant chemotherapy. Practices The clinical, pathological and follow-up information of 206 customers with triple negative cancer of the breast which obtained neoadjuvant chemotherapy with docetaxel combined with epirubicin coupled with cyclophosphamide regime within the division of Breast operation within the Third Affiliated Hospital of Zhengzhou University from January 2013 to December 2018 had been collected retrospectively. All had been feminine, old 28-71 (47.8±10.7) many years. In accordance with the whom category standard of acute and subacute toxicity of anticancer drugs, the customers had been divided into 98 instances within the moderate team (0-Ⅱ level) and 108 instances when you look at the serious group (Ⅲ-Ⅳ level) in line with the level of bone marrow suppression after chemotherapy. The standard clinicopathological features, pathological complete remission rate (PCR) and unbiased remission rate (ORR) of the two group group, severe myelosuppression group had much better disease-free success prognosis (HR=0.571, 95%CI 0.349-0.934). Conclusion The prognosis of grade Ⅲ/Ⅳ myelosuppression is way better legacy antibiotics than grade 0/Ⅰ/Ⅱ myelosuppression in clients with triple-negative cancer of the breast during neoadjuvant chemotherapy with TEC routine, which will be ideal for judging effectiveness.Objective to analyze the clinical efficacy for the modified Latarjet procedure in the treatment of recurrent anterior subluxation for the occult hepatitis B infection neck by “coaxial co-arc” reconstruction for the glenoid cavity. Techniques The medical data of 103 instances (106 arms) of recurrent anterior dislocation associated with the shoulder admitted to the First Affiliated Hospital regarding the Army Military Medical University from January 2005 to December 2020 were retrospectively examined. Out of these situations, 84 were guys and 19 were females; 31 with left-sided accidents while 75 with right-sided accidents, with a mean age of (29.4±11.5) many years (16-61 years). The preoperative anterior concern test was good, and a modified Latarjet procedure had been made use of to reconstruct the shoulder glenoid problem through a “coaxial co-arc”. The Rowe rating, easy shoulder test (SST) score, and artistic analogue scale (VAS) rating of discomfort were used to assess the shoulder’s function. Variables for instance the Q-VD-Oph nmr postoperative shoulder recurrent dislocation rate, shoulder body age cases of recurrent anterior shoulder dislocation, with reduced recurrence rates, reasonable modification prices and reduced incidence of osteoarthritis.Objective To study the result of ultrasonic-guided serratus jet block combined with pectoral nerve block Ⅰ on postoperative analgesia after radical mastectomy. Practices A total of 30 patients, all female, aged [M (Q1, Q3)] 53 (43, 62) years old, which underwent radical mastectomy in Beijing Tongren Hospital from May to August 2021 had been chosen. The clients were divided into two groups (n=15 in each group) making use of a random number table basic anesthesia alone+patient controlled intravenous analgesia (PCIA) group (control team) and serratus plane block along with pectoral neurological block Ⅰ before general anesthesia+PCIA team (blended team). Numerical rating scale (NRS) at rest in both teams were recognized into the post anesthesia care product (PACU) and 4, 8, 12, 24, 36 and 48 h after operation. The full time of very first pain, the time of very first pressing for the automatic analgesic unit after the procedure, the dosage of remifentanil during operation, cumulative dosages of sufentanil at 24 h and 48 h postoperatively, and the occurrence of adverse effects had been all recorded. Outcomes The NRS scores in mixed group in the PACU and 4, 8, 12 and 24 h after surgery were (2.1±1.7), (1.7±1.5), (1.5±1.4), (1.5±1.3) and (1.7±1.3), correspondingly, although the NRS scores in control team at each and every time points had been (4.5±2.0), (3.2±1.4), (2.7±0.9), (2.8±0.9) and (2.4±0.8), respectively, as well as the NRS results in blended group were notably lower than those in control group (all P0.05). Conclusion Serratus jet block along with pectoral nerve block Ⅰ can effectively relieve postoperative pain, reduce steadily the significance of opioids, and reduce the occurrence of undesireable effects.Objective To explore the diagnostic efficacy of metagenomicnext-generation sequencing (mNGS) technique for pathogen diagnosis of intracranial disease after neurosurgery. Techniques Patients with suspected intracranial illness after neurosurgery who had been treated in Beijing Tiantan Hospital of Capital health University from May 2017 to October 2018 were selected.