In 2010, the European Commission recognised this need and funded a collaborative RTD/SME project under the Framework 7-Knowledge Based Bio-Economy (KBBE) Theme 2 Programme ‘Sustainable culture of marine microorganisms, algae and/or invertebrates for high value added products’. The scope of that project entitled ‘Sustainable Production of Biologically Active Molecules of Marine Based Origin’ (BAMMBO) is outlined. Although the Union is a global leader in many technologies, it faces increasing competition from traditional Selleck AZD4547 rivals and emerging economies alike and must therefore improve its innovation performance. For this reason innovation is placed

at the heart of a European Horizon 2020 Strategy wherein the challenge is to connect economic

performance to eco performance. This article provides a synopsis of the research activities of the BAMMBO project as they fit within the wider find more scope of sustainable environmentally conscientious marine resource exploitation for high-value biomolecules.”
“Heparins are widely used for prophylaxis and treatment of thromboembolic diseases. Besides bleeding complications, heparin-induced skin lesions are the most frequent unwanted adverse effects of subcutaneous heparin treatment. Evidence suggests that these lesions are more common than previously thought. Lesions are most frequently due to either allergic reactions or to possibly life-threatening heparin-induced thrombocytopenia. Early recognition and adequate treatment are highly important, because although both complications initially show a similar clinical picture, their treatment should be fundamentally different. Furthermore, risk factors associated with the patient, drug, and treatment regimen have been identified. MLN2238 order We review the clinical range of heparin-induced skin lesions, emphasise evidence and controversies in epidemiology, diagnosis, and differential diagnosis, and discuss the management of patients with these

skin lesions.”
“Background. It is important for doctors and patients to know what factors help recovery from depression. Our objectives were to predict the probability of sustained recovery for patients presenting with mild to moderate depression in primary care and to devise a means of estimating this probability on an individual basis.

Method. Participants in a randomized controlled trial were identified through general practitioners (GPs) around three academic centres in England. Participants were aged > 18 years, with Hamilton Depression Rating Scale (HAMD) scores 12-19 inclusive, and at least one physical symptom on the Bradford Somatic Inventory ( BSI). Baseline assessments included demographics, treatment preference, life events and difficulties and health and social care use. The outcome was sustained recovery, defined as HAMD score < 8 at both 12 and 26 week follow-up.