Long-term follow-up of the patients is therefore essential.[22] In conclusion, subcutaneous Deltarasin? leiomyosarcoma is a rare clinical Inhibitors,Modulators,Libraries entity. Clinical presentation may be non-specific. Physicians should be aware of the misleading features of the tumor in order to avoid delay in diagnosis and treatment. Early Inhibitors,Modulators,Libraries surgical resection with wide margins of at least 2 cm is the treatment of choice and has been reported to mostly influence the prognosis. However, the tumor has a high tendency to recur locally and metastasize. Recurrences may develop despite the initial wide surgical resection and administration of adjuvant radiation therapy. Long-term follow-up of the patients is mandatory. ACKNOWLEDGMENT The author would like to thank Dr Tsiambas E. from the Pathology Department for providing the histology slide.

Footnotes Source of Support: Nil Conflict of Interest: None declared
A 50-year-old male presented Inhibitors,Modulators,Libraries with a right side testicular swelling and right side inguinal lymph node enlargement since five months. Fine needle aspiration cytology of the inguinal lymph node showed cells having anisokaryosis, round vesicular nucleus, irregular nuclear border/nuclear clefts with scant cytoplasm. A diagnosis of NHL/metastatic deposits from testis was suggested. We received the orchiectomy specimen measuring 8 �� 6 �� 5 cm. External surface showed a raw area/breach Inhibitors,Modulators,Libraries in capsule measuring 6 �� 5 cm. Cut section showed a well-circumscribed grey-white tumor measuring 6 �� 3 cm with focal areas of hemorrhage [Figure 1]. Periphery of the tumor showed normal compressed testicular tissue.

Spermatic cord measured 9 �� 2 cm. Cut section was unremarkable. Figure 1 Grey-white tumor Inhibitors,Modulators,Libraries with adjacent compressed testis and epidydimis. Tumor shows a breach of the Brefeldin_A tunica albuginea at one end Microscopy showed a small round monotonous population of cells showing isokaryosis and scanty cytoplasm, arranged in sheets [Figures [Figures22 and and3].3]. The stroma in between showed scanty fibrovascular tissue. Amidst the tumor tissue were seen a few eosinophils. Areas of confluent necrosis were also seen. Differential diagnoses of seminoma and NHL were offered. Immunohistochemistry showed that the tumor cells were positive for CD 20 [Figure 4], and negative for CD 5, CD23 and Cyclin D1. Mib 1 proliferation index was 90%. There was immunoexpression for both kappa and lamda light chain. A final diagnosis of high-grade NHL of B-cell phenotype was considered.