Reoperations are common and may be useful in attenuating the inflammatory response and optimizing the immune response. References 1. Mazuski JE, Solomkin JS: Intra-abdominal infections. Surg Clin North Am 2009,89(2):421–437.PubMed 2. Babinchak T, Ellis-Grosse E, Dartois N, Rose GM, Loh E: The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical data.

Clin Infect Dis 2005,41(Suppl 5):S354-S367.PubMed 3. Merlino JI, Malangoni MA, Smith CM, Lange RL: Prospective randomized https://www.selleckchem.com/products/KU-55933.html trials affect the outcomes of intraabdominal infection. Ann Surg 2001,233(6):859–866.PubMedCentralPubMed 4. Mazuski JE, Sawyer RG, Nathens AB, DiPiro JT, Schein M, Kudsk KA, Yowler C: Therapeutic agents committee of the surgical infections society. The surgical infection society guidelines on antimicrobial therapy

for intra-abdominal infections: evidence for the recommendations. Surg Infect (Larchmt) 2002,3(3):175–233. 5. Sartelli M, Catena F, Ansaloni L, Leppaniemi A, Taviloglu ��-Nicotinamide cost K, van Goor H, Viale P, Lazzareschi DV, Coccolini F, Corbella D, de Werra C, Marrelli D, Colizza S, Scibè R, Alis H, Torer N, Navarro S, Sakakushev B, Massalou D, Augustin G, Catani M, Kauhanen S, Pletinckx P, Kenig J, di Saverio S, Jovine E, Guercioni G, Skrovina M, Diaz-Nieto R, Ferrero A, et al.: Complicated intra-abdominal infections in PF 01367338 Europe: a comprehensive review of the CIAO study. World J Emerg Surg 2012,7(1):36.PubMedCentralPubMed Ureohydrolase 6. LaRosa SP: Sepsis: Menu of new approaches replaces one therapy for all. Cleve Clin J Med 2002, 69:65–73.PubMed 7. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G: SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions

conference. Crit Care Med 2001,2003(31):1250–1256. 8. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: American college of chest physicians/society of critical care medicine consensus conference: definitions for sepsis and organ failure and guidlines for the use of innovative therapies in sepsis. Chest 1992, 101:1644–1655.PubMed 9. Jones AE, Yiannibas V, Johnson C, Kline JA: Emergency department hypotension predicts sudden unexpected in-hospital mortality: a prospective cohort study. Chest 2006, 130:941–946.PubMed 10. Esteban A, Frutos-Vivar F, Ferguson ND, Peñuelas O, Lorente JA, Gordo F, Honrubia T, Algora A, Bustos A, García G, Diaz-Regañón IR, de Luna RR: Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward. Crit Care Med 2007,35(5):1284–1289.PubMed 11.