Endoscopic drainage was done in 16 patients; 2 resolved, 11 had resolving WON and 2 had persistent WON. 24 patients required

surgery in total and 12 patients expired. Conclusion: Majority of fluid collections are acute necrotic Peptide 17 mouse collections (ANC) and majority of them developed WON. Pseudocyst occurs extremely rare in the natural history of acute pancreatitis. Infections and need for intervention were seen predominantly in patients with ANC and half of them can be managed conservatively. Key Word(s): 1. Acute pancreatitis; 2. Fluid collections; 3. Pseudocyst; 4. WON; Presenting Author: MALAY SHARMA Additional Authors: CHITRANSHU VASHISHTHA Corresponding Author: MALAY SHARMA Affiliations: Jaswant Rai Speciality Hospital; Institute of Liver & Biliary Sciences Objective: Acute Pancreatitis (AP) can occur due to presence of impacted small stones in prepapillary area. These stones can also migrate into pancreatic duct (PD). The aim of the study was to determine the role of Endoscopic ultrasound (EUS) in finding prepapillary and migrated intrapancreatic stone by EUS in AP (within first 48 hrs) where history and investigations failed to reveal a cause. Methods: 280 patients

of AP admitted from September 2005 to March 2013 underwent clinical evaluation and baseline biochemistry was done. Transabdominal ultrasonogram &/or CECT of abdomen was done. Patients with first attack of pancreatitis, where aetiology was not known and in whom EUS was done during the acute episode were included for analysis. Those with previous attacks of pancreatitis or with an established aetiology after these investigations were excluded. Obeticholic Acid Results: Out of 280 patients admitted with AP, 85 fulfilled the inclusion criteria. Endoscopic ultrasound was able to suggest the etiology in 46 patients. Gallbladder

stone related disease was found in 38 cases. 9 cases had prepapillary stone of CBD origin and 5 had PD stones which had migrated from CBD. Other causes included suprapapillary CBD stone (9), microlithiasis Ponatinib solubility dmso of gall bladder (1), sludge in gall bladder (13) and microlithiasis of common bile duct (1). Conclusion: Early EUS has different therapeutic impact as compared to EUS after 4 weeks in AP. Dilated PD in AP may be due to impacted or migrated CBD stones which can be easily identified by EUS. When a stone migrates into PD it can dilate for a while but the duct becomes normal subsequently in most of the cases. EUS should be done early to manage a subgroup of cases of AP. Key Word(s): 1. Acute Pancreatittis; Presenting Author: RAJESH GUPTA Additional Authors: SUNIL SHENVI, SHRUTI HS, DEEPAK BHASIN, SURINDER RANA Corresponding Author: RAJESH GUPTA Affiliations: PGIMER Objective: Debilitating abdominal pain remains the most common presentation of chronic pancreatitis and the treatment remains challenging. This study analyzed the outcome of surgery in patients with chronic pancreatitis.